LundPharma

Tofu Extract (DT56a, Tofupill^®) Offers Benefits to Postmenopausal Women
12-Month Clinical Study Evaluating Efficacy and Safety of Dietary Supplement for Menopausal Symptoms Helps Distinguish DT56a (Tofupill^®) as a Novel, Effective Approach to Relieving Menopausal Symptoms and Building Bone Density.
A newly published clinical study, "Efficacy and safety of standard versus low-dose Tofupill^® (DT56a) for the treatment of menopausal symptoms"; I. Yoles et al, in the Journal of Clinical & Experimental Obstetrics & Gynecology (2004;31(2):123-126), the report on this phytoSERM, finds that Tofupill^® (DT56a), can safely and effectively relieve menopausal symptoms in menopausal women while building bone density (BMD), without any adverse side effects. This is good news for menopausal women looking for non-medical relief following on the heels of the recent JAMA report (July 7, 2004), which concluded that soy protein containing sole isoflavone was not effective in improving BMD, cognitive function or plasma lipids in healthy postmenopausal women.

Unlike soy isoflavone products, Tofupill^®/Femarelle™ is a potent, non-estrogen phyto selective estrogen receptor modulator (SERM) that has been shown through numerous studies to safely and effectively relieve the hot flashes, sleep disturbances and headaches - symptoms that plague many menopausal women. Tofupill^®/Femarelle™ (DT56a) increaseases bone mineral density in postmenopausal women, without affecting more sensitive tissues, such as the breast and uterus.
DT56a, the active substance in Tofupill^®/Femarelle™, is manufactured with a unique enzymatic process of isolation to ensure that the whole phytoestrogen family of compounds – all 56 components, as is found naturally in the tofu, remains in their naturally intact form. Other soy supplements sold are extracted isoflavones, and are not phytoSERMS.

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Overview of Tofupill^® on menopausal Symptoms

All studies of Tofupill^® point to the same direction. Women with menopausal problems get fast relief (average 5-7 days) with Tofupill. Hot flushes were relieved in 76% of the patients. Some other results are as follows:

Positive feedback overall 96%
Reduction of headaches 68%
Reduction of joint and muscle discomfort 70%
Reduction of night sweating 68%
Reduction of heart palpitations 77%
Reduction of sleep disturbances 69%
Reduction of nervousness 56%
Increase in sexual desire (libido) 68%

82% of women felt stable improvement when continuing taking Tofupill^®.

8/21/2003
Menopause fact:
The medical term “Menopause” means the time when menstruation stops. Usually, this happens between the ages of 45 and 55, but menopause can occur earlier or later.

8/21/2003
Menopause fact:
Menopause is not a disease but a natural biologic process representing the end of menstruation.

8/21/2003
Menopause fact:
The loss of estrogen is primarily responsible for menopausal symptoms, which can be divided into 3 categories: Vasomotor symptoms: such as hot flushes. Psychological symptoms: such as mood swings, irritability, fatigue. Physiological/metabolic symptoms: such as vaginal dryness. There is an increase of bone loss and an increase in cardio vascular diseases.

8/21/2003
Menopause fact:
80% of women of menopausal age suffer from menopausal symptoms; the most common ones are hot flashes and sleep disturbances.

8/21/2003
Menopause fact:
All women go through a process of increased loss of bone mineral density following the natural decline in estrogen levels.